HUGO ID Detailed Result 10886


HUGO ID 10886
Symbol SIRT2
Name sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
#Occurrence 5
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
16227974SIR2SIR-21.3melanogaster and Caenorhabditis elegans overexpression of the NAD-dependent histone deacetylase SIR-2 results in an increased lifespan 48 49 
16227974SIR2SIR-21.3The closest mammalian orthologue of SIR-2 is SIRT1 and it is presently not known whether overexpression 
16227974SIR2Sir21.3For instance yeast Sir2 seems to be important in protecting cells from accumulation of 
16227974SIR2SIR-21.3model of the neurodegenerative condition Huntington's disease upregulated expression of SIR-2 increased neuronal survival 54 
16227974SIR2SIR-21.3has also been recently proposed to increase the activity of SIR-2 (Ref Ref 55