HUGO ID Detailed Result 10417

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
11679167	ubiquitin	ubiquitin	1.0	in s. cerevisiae several components of the ubiquitin 26s proteasome pathway and vacuolar proteases are induced by hydrogen peroxide godon et al. 1998 ; lee et al. 1999 which is consistent with the involvement of these proteolytic pathways in the degrad
12663085	ubiquitin	ubiquitin	1.0	protein cross linkage results in aggregates which then form intracellular protease resistant and ubiquitin proteasome resistant deposits consequently inhibiting the intracellular transport of materials.
12663085	ubiquitin	ubiquitin	1.0	neuronal hyaline inclusions nhis abnormal intracellular structures that appear in the soma and neurites of some of the surviving lower motor neurons and contain ubiquitin and phosphorylated neurofilament protein are the characteristic markers of fals with sod 1 mutations.
12893007	ubiquitin	ubiquitin	1.0	another important observation is accumulation of abnormal ubiquitin conjugated proteins in affected neurons suggesting dysfunction of the proteasome proteolytic system in these cells [ shringarpure et al ] .
12893007	ubiquitin	ubiquitin	1.0	accumulation of abnormal ubiquitin conjugated proteins in affected neurons in ad suggests dysfunction of proteasome system while co existence of hne immunoreactivity in the same cells suggests the essential role of oxidative damage in
12893007	ubiquitin	ubiquitin	1.0	hne is toxic for p19 cells causing cross linking of tau into high molecular weight substances that are conjugated with ubiquitin [ montine et al ] .
12893007	ubiquitin	ubiquitin	1.0	the same inclusions contain epitopes of ubiquitin and phosphorylated neurofilament protein [ shibata et al ] .
12909279	ubiquitin	ubiquitin	1.0	in fact it is known that neurons and astrocytes of sals patients contain cytoplasmic aggregates that show immunoreactivity for sod1 and ubiquitin; similar inclusion bodies were also observed in sod1 linked fals patients [ 12 ].
14739060	ubiquitin	ubiquitin	1.0	g93a transgenic mouse [ 46 50 47 48 and 49 ]. _amp_#x2022; protein misfolding and aggregates: for example of a_amp_#x3b2; 42 for ad [ 43 ]. _amp_#x2022; proteasome dysfunction on ubiquinited material ubiquitin forms covalent bonds with other protein in order to mark them for degradation by an atp dependent non lysosomial proteolytic system i.e proteasome . _amp_#x2022; oxidative stress mitochondria dysfunc
14739060	ubiquitin	ubiquitin	1.0	tion of proteins: microtubular tau protein for the former accumulation of several aggregated proteins _amp_#x3b2; amyloid especially its toxic form a_amp_#x3b2; 42 apoe [ 43 ] hyperphosphorylated tau ubiquitin presenilin 1_amp_#xa0;and 2 with an inflammatory reaction around the deposit of _amp_#x3b2; amyloid for the latter [ 38 ].
14739060	ubiquitin	ubiquitin	1.0	as demonstrated in transgenic mouse this abnormal protein is cleaved to fragments conjugated with ubiquitin; which aggregate forming neuronal intra nuclear inclusions.
15105254	ubiquitin	ubiquitin	1.0	in parkinson's disease pd mitochondrial toxins and perturbed ubiquitin dependent proteolysis may impair atp production and increase oxyradical production and maos.
15896810	ubiquitin	ubiquitin	1.0	some of the known hsps include ubiquitin hsp10 hsp27 hsp32 or ho 1 hsp47 hsp60 hsc70 hsp70 or hsp72 hsp90 and hsp100/105.
15896810	ubiquitin	ubiquitin	1.0	ubiquitin is one of the smallest hsps and is expressed throughout brain in response to ischemia.
16043017	ubiquitin	ubiquitin	1.0	these proteins are sod1 translationally controlled tumor protein tctp ubiquitin carboxyl terminal hydrolase l1 uch l1 and possibly b crystallin.
16043017	ubiquitin	ubiquitin	1.0	the proteinaceous inclusions found in tissues from als patients [23] [24] and [25] and msod transgenic mice [22] and [26] reportedly are rich in msod ubiquitin and neurofilament proteins.
16043017	ubiquitin	ubiquitin	1.0	ubiquitin carboxyl terminal hydrolase l1 uch l1 assay
16043017	ubiquitin	ubiquitin	1.0	uch l1 belongs to a family of ubiquitin carboxyl terminal hydrolases that play important roles in the ubiquitin_amp_#x2013;proteolytic pathway [71] .
16043017	ubiquitin	ubiquitin	1.0	uch ls then recycle ubiquitin from ubiquitinated protein complexes or polyubiquitin chains by cleaving the amide linkage next to the c terminal glycine of ubiquitin [72] .
16043017	ubiquitin	ubiquitin	1.0	moreover crystallins were recruited to aggregates when cells were treated with proteasome inhibitor [88] and the degradation of b crystallin along with ubiquitin conjugation was decreased in bovine lens epithelial cells when b crystallin was oxidized [89] .
16043017	ubiquitin	ubiquitin	1.0	ubiquitin protein epitopes and b crystallin are found in fibrillar neuronal inclusions in the cortex of sporadic als patients [79] [80] [81] and [91] .
16050975	ubiquitin	ubiquitin	1.0	ons are bunina bodies round eosinophilic inclusions containing a homogeneous granular matrix surrounded by vesicular and tubular structures tomonaga et al. 1978 and skein like inclusions that contain ubiquitin and are comprised of bundles of 15_amp_#x2013;20 nm thick neurofilaments migheli et al. 1990 and sasaki and maruyama 1992 .
17191135	ubiquitin	ubiquitin	1.0	some of the known hsps include ubiquitin hsp10 hsp27 hsp32 or ho 1 hsp47 hsp60 hsc70 hsp70 or hsp72 hsp90 and hsp100/105.
17191135	ubiquitin	ubiquitin	1.0	chip_amp_#8217;s is a ubiquitin e3 ligase that can collaborate with molecular chaperones to facilitate protein folding and prevent protein aggregation.