# PathwayID;Name hsa04010;MAPK signaling pathway - Homo sapiens (human) hsa04210;Apoptosis - Homo sapiens (human) hsa04510;Focal adhesion - Homo sapiens (human) hsa01510;Neurodegenerative Diseases - Homo sapiens (human) 168256;Signaling in Immune system hsa04620;Toll-like receptor signaling pathway - Homo sapiens (human) hsa05215;Prostate cancer - Homo sapiens (human) hsa05222;Small cell lung cancer - Homo sapiens (human) hsa05210;Colorectal cancer - Homo sapiens (human) hsa04012;ErbB signaling pathway - Homo sapiens (human) 166520;Signalling by NGF hsa04060;Cytokine-cytokine receptor interaction - Homo sapiens (human) hsa05212;Pancreatic cancer - Homo sapiens (human) hsa04370;VEGF signaling pathway - Homo sapiens (human) hsa04910;Insulin signaling pathway - Homo sapiens (human) hsa05214;Glioma - Homo sapiens (human) 109581;Apoptosis 73894;DNA Repair hsa04660;T cell receptor signaling pathway - Homo sapiens (human) hsa04664;Fc epsilon RI signaling pathway - Homo sapiens (human) hsa05218;Melanoma - Homo sapiens (human) hsa05220;Chronic myeloid leukemia - Homo sapiens (human) 109582;Hemostasis hsa05223;Non-small cell lung cancer - Homo sapiens (human) hsa04650;Natural killer cell mediated cytotoxicity - Homo sapiens (human) hsa04912;GnRH signaling pathway - Homo sapiens (human) 187037;TRKA signalling from the plasma membrane hsa05030;Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human) hsa04670;Leukocyte transendothelial migration - Homo sapiens (human) hsa05213;Endometrial cancer - Homo sapiens (human) hsa04730;Long-term depression - Homo sapiens (human) hsa04115;p53 signaling pathway - Homo sapiens (human) hsa04630;Jak-STAT signaling pathway - Homo sapiens (human) hsa05221;Acute myeloid leukemia - Homo sapiens (human) hsa04810;Regulation of actin cytoskeleton - Homo sapiens (human) hsa04916;Melanogenesis - Homo sapiens (human) hsa04640;Hematopoietic cell lineage - Homo sapiens (human) 140192;Metabolism of xenobiotics hsa04540;Gap junction - Homo sapiens (human) hsa04310;Wnt signaling pathway - Homo sapiens (human) 109606;Intrinsic Pathway for Apoptosis hsa04020;Calcium signaling pathway - Homo sapiens (human) hsa05211;Renal cell carcinoma - Homo sapiens (human) hsa04150;mTOR signaling pathway - Homo sapiens (human) hsa05120;Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) hsa04940;Type I diabetes mellitus - Homo sapiens (human) hsa00190;Oxidative phosphorylation - Homo sapiens (human) hsa04530;Tight junction - Homo sapiens (human) hsa04662;B cell receptor signaling pathway - Homo sapiens (human) 69278;Cell Cycle, Mitotic hsa04720;Long-term potentiation - Homo sapiens (human) hsa05010;Alzheimer's disease - Homo sapiens (human) 163200;Electron Transport Chain hsa05219;Bladder cancer - Homo sapiens (human) 74752;Signaling by Insulin receptor 15869;Nucleotide metabolism 198203;PI3K/AKT signalling hsa00480;Glutathione metabolism - Homo sapiens (human) 202403;TCR signaling 162906;HIV Infection 75178;Formation of Platelet plug hsa04920;Adipocytokine signaling pathway - Homo sapiens (human) hsa05040;Huntington's disease - Homo sapiens (human) hsa04930;Type II diabetes mellitus - Homo sapiens (human) 168898;Toll Receptor Cascades 69620;Cell Cycle Checkpoints hsa04612;Antigen processing and presentation - Homo sapiens (human) 202424;Downstream TCR signaling hsa04070;Phosphatidylinositol signaling system - Homo sapiens (human) hsa00350;Tyrosine metabolism - Homo sapiens (human) hsa00010;Glycolysis / Gluconeogenesis - Homo sapiens (human) hsa04080;Neuroactive ligand-receptor interaction - Homo sapiens (human) 73890;Double-Strand Break Repair 168249;Innate Immunity Signaling hsa00620;Pyruvate metabolism - Homo sapiens (human) 69306;DNA Replication 74160;Gene Expression 177929;Signaling by EGFR hsa00251;Glutamate metabolism - Homo sapiens (human) 163685;Integration of energy metabolism hsa00590;Arachidonic acid metabolism - Homo sapiens (human) 74751;Insulin receptor signalling cascade hsa05060;Prion disease - Homo sapiens (human) 71291;Metabolism of amino acids hsa04350;TGF-beta signaling pathway - Homo sapiens (human) 73923;Lipid and lipoprotein metabolism 202733;Cell surface interactions at the vascular wall 77389;IRS-related events hsa05216;Thyroid cancer - Homo sapiens (human) 167044;Signalling to RAS 73951;Homologous recombination repair of replication-independent double-strand breaks 73847;Purine metabolism 168180;TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha/beta cascade 157579;Telomere Maintenance hsa04110;Cell cycle - Homo sapiens (human) 73888;Homologous Recombination Repair hsa04520;Adherens junction - Homo sapiens (human) 112399;IRS-mediated signalling hsa05020;Parkinson's disease - Homo sapiens (human) 187687;Signalling to ERKs hsa00360;Phenylalanine metabolism - Homo sapiens (human) 69242;S Phase 71406;Pyruvate metabolism and TCA cycle 168164;Toll Like Receptor 3 (TLR3) Cascade hsa00230;Purine metabolism - Homo sapiens (human) hsa00380;Tryptophan metabolism - Homo sapiens (human) 73887;Death Receptor Signalling hsa00340;Histidine metabolism - Homo sapiens (human) hsa00790;Folate biosynthesis - Homo sapiens (human) 140191;Phase 1 functionalization hsa00562;Inositol phosphate metabolism - Homo sapiens (human) hsa00650;Butanoate metabolism - Homo sapiens (human) 74159;Transcription hsa04360;Axon guidance - Homo sapiens (human) 162909;Host Interactions of HIV factors 76005;Response to elevated platelet cytosolic Ca++ 74231;Purine biosynthesis hsa05050;Dentatorubropallidoluysian atrophy (DRPLA) - Homo sapiens (human) hsa00260;Glycine, serine and threonine metabolism - Homo sapiens (human) hsa04120;Ubiquitin mediated proteolysis - Homo sapiens (human) 109607;Extrinsic Pathway for Apoptosis 111471;Apoptotic factor-mediated response 69239;Synthesis of DNA hsa00561;Glycerolipid metabolism - Homo sapiens (human) 163359;Glucagon signaling in metabolic regulation 194840;Rho GTPase cycle 170984;ARMS-mediated activation 202131;Metabolism of nitric oxide 114608;Platelet degranulation 194315;Signaling by Rho GTPases 140534;Caspase-8 is formed from procaspase-8 169893;Prolonged ERK activation events 114509;Platelet activation triggers 170968;Frs2-mediated activation hsa00252;Alanine and aspartate metabolism - Homo sapiens (human) 71403;Citric acid cycle (TCA cycle) 111459;Activation of caspases through apoptosome-mediated cleavage hsa00220;Urea cycle and metabolism of amino groups - Homo sapiens (human) hsa05130;Pathogenic Escherichia coli infection - EHEC - Homo sapiens (human) 187706;Signalling to p38 via RIT and RIN 114611;Exocytosis of Alpha granule 75157;FasL/ CD95L signaling 76002;Platelet Activation hsa01430;Cell Communication - Homo sapiens (human) 71408;Metabolism of small molecules hsa00860;Porphyrin and chlorophyll metabolism - Homo sapiens (human) 69615;G1/S DNA Damage Checkpoints 71387;Metabolism of carbohydrates hsa00330;Arginine and proline metabolism - Homo sapiens (human) hsa00020;Citrate cycle (TCA cycle) - Homo sapiens (human) hsa05131;Pathogenic Escherichia coli infection - EPEC - Homo sapiens (human) 111461;Cytochrome c-mediated apoptotic response 77388;SHC-related events 198725;Nuclear Events (kinase and transcription factor activation) 69416;Activation of Pro-Caspase 8 164378;PKA activation in glucagon signalling hsa00410;beta-Alanine metabolism - Homo sapiens (human) 69304;Regulation of DNA replication hsa00680;Methane metabolism - Homo sapiens (human) 194138;Signaling by VEGF 111748;Synthesis of deoxyribonucleoside 5'-diphosphates from ribonucleoside 5'-diphosphates 69052;Switching of origins to a post-replicative state hsa04512;ECM-receptor interaction - Homo sapiens (human) 156902;Peptide chain elongation 76010;Homologous DNA pairing and strand exchange 69580;p53-Dependent G1/S DNA damage checkpoint 69190;DNA strand elongation 72766;Translation 195399;VEGF binds to VEGFR leading to receptor dimerization 112410;SHC-mediated signalling hsa02010;ABC transporters - General - Homo sapiens (human) 162587;HIV Life Cycle 73848;Pyrimidine metabolism 70326;Glucose metabolism hsa04320;Dorso-ventral axis formation - Homo sapiens (human) 74226;ATP formation 198323;AKT phosphorylates targets in the cytosol 156842;Eukaryotic Translation Elongation 162594;Early Phase of HIV Life Cycle 111463;SMAC binds to IAPs 111458;Formation of apoptosome 109704;PI3K Cascade hsa00930;Caprolactam degradation - Homo sapiens (human) 203615;eNOS activation 75154;Recruitment of repair and signaling proteins to double-strand breaks 194306;Neurophilin interactions with VEGF and VEGFR 71397;Oxidative decarboxylation of pyruvate to acetyl CoA by pyruvate dehydrogenase 180292;Gab1 signalosome hsa00980;Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human) 69206;G1/S Transition hsa00240;Pyrimidine metabolism - Homo sapiens (human) 199418;Negative regulation of the PI3K/AKT network 69481;G2/M Checkpoints 114452;Activation of BH3-only proteins 194313;VEGF ligand-receptor interactions 112412;SOS-mediated signalling 109869;MAP kinase cascade hsa00500;Starch and sucrose metabolism - Homo sapiens (human) 111469;SMAC-mediated apoptotic response 111464;SMAC-mediated dissociation of IAP:caspase complexes 76003;Presynaptic phase of homologous DNA pairing and strand exchange 75071;mRNA Processing hsa04514;Cell adhesion molecules (CAMs) - Homo sapiens (human) 75893;TNF signaling 69563;p53-Dependent G1 DNA Damage Response 203765;eNOS activation and regulation 204174;Regulation of pyruvate dehydrogenase complex (PDC) hsa00120;Bile acid biosynthesis - Homo sapiens (human) 198753;ERK/MAPK targets 68949;Orc1 removal from chromatin 69300;Removal of licensing factors from origins 196836;Vitamin C (ascorbate) metabolism 69166;Removal of the Flap Intermediate hsa00960;Alkaloid biosynthesis II - Homo sapiens (human) 163210;Formation of ATP by chemiosmotic coupling 202670;ERKs are inactivated 111807;Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin hsa04340;Hedgehog signaling pathway - Homo sapiens (human) 68867;Assembly of the pre-replicative complex hsa00280;Valine, leucine and isoleucine degradation - Homo sapiens (human) 69202;Cyclin E associated events during G1/S transition 210993;Tie2 Signaling 72163;mRNA Splicing - Major Pathway 72613;Eukaryotic Translation Initiation 69236;G1 Phase 70894;Valine catabolism 110373;Resolution of AP sites via the multiple-nucleotide patch replacement pathway hsa00641;3-Chloroacrylic acid degradation - Homo sapiens (human) hsa00910;Nitrogen metabolism - Homo sapiens (human) 173107;Binding and entry of HIV virion 111742;Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (glutaredoxin) 111752;Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin 75153;Apoptotic execution phase 73857;RNA Polymerase II Transcription 187015;Activation of TRKA receptors 75983;Formation and Maturation of mRNA Transcript 168254;Influenza Infection hsa00100;Biosynthesis of steroids - Homo sapiens (human) 70171;Glycolysis 112295;Elongation and Processing of Capped Transcripts 156590;Glutathione conjugation hsa00290;Valine, leucine and isoleucine biosynthesis - Homo sapiens (human) 157212;A third proteolytic cleavage releases NICD 74219;dGTP formation 114696;Thrombin-activated activation cascade 76043;Elongation of Intron-Containing Transcripts and co-transcriptional mRNA splicing 156580;Phase II conjugation hsa00430;Taurine and hypotaurine metabolism - Homo sapiens (human) hsa04740;Olfactory transduction - Homo sapiens (human) 110362;Removal of DNA patch containing abasic residue 70268;Cori Cycle (interconversion of glucose and lactate) hsa00630;Glyoxylate and dicarboxylate metabolism - Homo sapiens (human) 140179;Amine Oxidase reactions hsa00564;Glycerophospholipid metabolism - Homo sapiens (human) 75815;Ubiquitin-dependent degradation of Cyclin D 174414;Processive synthesis on the C-strand of the telomere 141333;Monoamines are oxidized to aldehydes, producing NH3 and H2O2 198933;Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 72187;mRNA 3'-end processing 112296;Post-Elongation Processing of Intron-Containing pre-mRNA 164952;The role of Nef in HIV-1 replication and disease pathogenesis 69229;Ubiquitin-dependent degradation of Cyclin D1 83572;MRN complex relocalizes to nuclear foci 157279;3' -UTR-mediated translational regulation 114665;G-protein cascades 202433;Generation of second messenger molecules hsa00940;Phenylpropanoid biosynthesis - Homo sapiens (human) hsa00720;Reductive carboxylate cycle (CO2 fixation) - Homo sapiens (human) 168927;Viral dsRNA:TLR3:TRIF Complex Activates RIP1 hsa04140;Regulation of autophagy - Homo sapiens (human) 114604;Collagen-mediated activation cascade 192076;Steroid metabolism 75177;Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks 112168;Processing of Capped pre-mRNA 69002;DNA Replication Pre-Initiation 75924;Processing of DNA ends prior to end rejoining 69186;Lagging Strand Synthesis 72737;Cap-dependent Translation Initiation 70614;Aspartate, asparagine, glutamate, and glutamine metabolism 210990;PECAM1 interactions 198693;AKT phosphorylates targets in the nucleus 109688;Cleavage of Growing Transcript in the Termination Region 71384;Ethanol catabolism 73889;Nonhomologous End-joining (NHEJ) hsa00040;Pentose and glucuronate interconversions - Homo sapiens (human) 68874;M/G1 Transition hsa00071;Fatty acid metabolism - Homo sapiens (human) 76044;Post-Elongation Processing of the Transcript 111447;Activation of BAD and translocation to mitochondria 73856;RNA Polymerase II Transcription Termination 72202;Transport of Mature Transcript to Cytoplasm 69231;Cyclin D associated events in G1 72764;Eukaryotic Translation Termination 111747;Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and glutaredoxin 162592;Integration of provirus 75158;TRAIL signaling 180786;Extension of Telomeres 74230;dATP formation hsa03320;PPAR signaling pathway - Homo sapiens (human) hsa05217;Basal cell carcinoma - Homo sapiens (human) 74749;Signal attenuation 111457;Release of apoptotic factors from the mitochondria 174417;Telomere C-strand (Lagging Strand) Synthesis 111465;Cleavage of cellular proteins by active caspases 176187;Activation of ATR in response to replication stress hsa05110;Cholera - Infection - Homo sapiens (human) 70895;Branched-chain amino acid catabolism 171007;p38MAPK events 73933;Resolution of Abasic Sites (AP sites) 111804;Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (thioredoxin) 72172;mRNA Splicing 174437;Removal of the Flap Intermediate from the C-strand hsa00640;Propanoate metabolism - Homo sapiens (human) 69656;Cyclin A:Cdk2-associated events at S phase entry hsa00600;Sphingolipid metabolism - Homo sapiens (human) 69183;Processive synthesis on the lagging strand 187024;NGF-independant TRKA activation hsa04330;Notch signaling pathway - Homo sapiens (human) hsa00760;Nicotinate and nicotinamide metabolism - Homo sapiens (human) 167021;PLC-gamma1 signalling 196849;Metabolism of water-soluble vitamins and cofactors 112409;ERK activation 73648;Pyrimidine biosynthesis (interconversion) 111751;Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (thioredoxin) 69541;Stabilization of p53 196854;Metabolism of vitamins and cofactors 76000;Assembly of the RAD51-ssDNA nucleoprotein complex 157118;Signaling by Notch 73884;Base Excision Repair 72706;GTP hydrolysis and joining of the 60S ribosomal subunit 72689;Formation of a pool of free 40S subunits 72203;Processing of Capped Intron-Containing Pre-mRNA 156827;L13a-mediated translational silencing of Ceruloplasmin expression 109970;Global Genomic NER (GG-NER) 168769;BoNT Light Chain Types B, D, and F cleave VAMP/Synaptobrevin hsa00550;Peptidoglycan biosynthesis - Homo sapiens (human) 174800;Chylomicron-mediated lipid transport 168273;Influenza Viral RNA Transcription and Replication 73728;RNA Polymerase I Promoter Opening 70172;Phosphorylase kinase activates glycogen phosphorylase 109979;Gap-filling DNA repair synthesis and ligation in TC-NER 191650;Regulation of gap junction activity 168176;Toll Like Receptor 5 (TLR5) Cascade 166207;S6K1-mediated signalling 69610;p53-Independent DNA Damage Response 190241;FGFR2 ligand binding and activation hsa00903;Limonene and pinene degradation - Homo sapiens (human) 194068;Metabolism of bile acids and bile salts 74969;Gap-filling DNA repair synthesis and ligation in GG-NER 168255;Influenza Life Cycle 72662;Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 140180;COX reactions 199920;CREB phosphorylation 202427;Phosphorylation of CD3 and TCR zeta chains 74744;SHC activation 114592;Collagen adhesion via alpha 2 beta 1 glycoprotein 174403;Glutathione synthesis 202430;Translocation of ZAP-70 to Immunological synapse 188108;MyD88 Cascade (Murine) 164843;2-LTR circle formation hsa00450;Selenoamino acid metabolism - Homo sapiens (human) hsa00310;Lysine degradation - Homo sapiens (human) 190375;FGFR2c ligand binding and activation 190370;FGFR1b ligand binding and activation 70108;Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+ 73621;Pyrimidine catabolism hsa04950;Maturity onset diabetes of the young - Homo sapiens (human) hsa00053;Ascorbate and aldarate metabolism - Homo sapiens (human) 166208;mTORC1-mediated signalling 112297;Post-Elongation Processing of Intronless pre-mRNA 190242;FGFR1 ligand binding and activation 159236;Transport of Mature mRNA derived from an Intron-Containing Transcript 190236;Signaling by FGFR 180897;Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization 70263;Gluconeogenesis 190373;FGFR1c ligand binding and activation 68962;Activation of the pre-replicative complex hsa00950;Alkaloid biosynthesis I - Homo sapiens (human) 75108;Activation, myristolyation of BID and translocation to mitochondria 72695;Formation of the ternary complex, and subsequently, the 43S complex hsa03030;DNA replication - Homo sapiens (human) 74257;Xanthine formation 166058;MyD88 cascade 187042;TRKA activation by NGF 164938;Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 114508;Phospholipase-mediated signalling hsa00770;Pantothenate and CoA biosynthesis - Homo sapiens (human) 171306;Packaging Of Telomere Ends 167826;The fatty acid cycling model 162585;Uncoating of the HIV Virion 177504;Retrograde neurotrophin signalling 83542;ATM mediated response to DNA double-strand break 168142;Toll Like Receptor 10 (TLR10) Cascade 168782;Proteolytic cleavage of SNARE complex proteins 174824;Lipoprotein metabolism 168188;Toll Like Receptor TLR6:TLR2 Cascade 114516;Disinhibition of SNARE formation 112407;RAF phosphorylates MEK 159234;Transport of Mature mRNAs Derived from Intronless Transcripts 72165;mRNA Splicing - Minor Pathway 71336;Pentose phosphate pathway (hexose monophosphate shunt) 168799;Botulinum neurotoxicity 190376;FGFR ligand binding and activation 74713;IRS activation 140187;P450 Prostaglandin isomerizations 70845;Isoleucine catabolism 181438;Toll Like Receptor 2 Cascade 180689;APOBEC3G mediated resistance to HIV-1 infection 159231;Transport of Mature mRNA Derived from an Intronless Transcript 71037;Oxidative decarboxylation of alpha-ketoadipate to glutaryl CoA by alpha-ketoglutarate dehydrogenase 69091;Polymerase switching 71383;Acetate, ATP, and coenzyme A react to form acetyl CoA, AMP, and pyrophosphate 110049;MEK activation 168325;Viral Messenger RNA Synthesis hsa00624;1- and 2-Methylnaphthalene degradation - Homo sapiens (human) 73930;Base-free sugar-phosphate removal via the single-nucleotide replacement pathway 72702;Ribosomal scanning and start codon recognition 180534;Vpu mediated degradation of CD4 165159;mTOR signalling 167590;Nef Mediated CD4 Down-regulation 73927;Depurination 164944;Nef and signal transduction hsa00471;D-Glutamine and D-glutamate metabolism - Homo sapiens (human) 69109;Leading Strand Synthesis 68886;M Phase 176033;Interactions of Vpr with host cellular proteins hsa04614;Renin-angiotensin system - Homo sapiens (human) 168179;Toll Like Receptor TLR1:TLR2 Cascade 71064;Lysine catabolism 166187;Mitochondrial Uncoupling Proteins 114664;G alpha 12 cascade 71338;Ethanol is oxidized by NAD+ to form acetaldehyde, NADH, and H+ hsa00740;Riboflavin metabolism - Homo sapiens (human) 69601;Ubiquitin Mediated Degradation of Phosphorylated Cdc25A hsa00460;Cyanoamino acid metabolism - Homo sapiens (human) 70525;Alanine metabolism 114294;Activation, translocation and oligomerization of BAX 162589;Reverse Transcription of HIV RNA 70853;Oxidative decarboxylation of alpha-ketoisovalerate to isobutyryl-CoA by branched-chain alpha-ketoacid dehydrogenase hsa00361;gamma-Hexachlorocyclohexane degradation - Homo sapiens (human) 69613;p53-Independent G1/S DNA damage checkpoint 164385;G(s)-alpha mediated events in glucagon signalling 114711;vWF interaction with collagen 77378;Formation of Cytosolic Glycerol-3-phosphate 168181;Toll Like Receptor 7/8 (TLR7/8) Cascade 190239;FGFR3 ligand binding and activation 110056;ERK1 activation hsa03022;Basal transcription factors - Homo sapiens (human) 69017;CDK-mediated phosphorylation and removal of Cdc6 190371;FGFR3b ligand binding and activation 195721;Signaling by Wnt 68875;Mitotic Prophase 164525;Plus-strand DNA synthesis 166054;Activated TLR4 signalling 72649;Translation initiation complex formation 163358;PKA-mediated phosphorylation of key metabolic factors 114593;Collagen adhesion via Gp IV hsa04742;Taste transduction - Homo sapiens (human) 68827;CDT1 association with the CDC6:ORC:origin complex 77595;Processing of Intronless Pre-mRNAs hsa00130;Ubiquinone biosynthesis - Homo sapiens (human) 73929;Base-Excision Repair, AP Site Formation 139910;Activation of BMF and translocation to mitochondria hsa01030;Glycan structures - biosynthesis 1 - Homo sapiens (human) 109977;Repair synthesis for gap-filling by DNA polymerase in TC-NER 192456;Digestion of dietary lipid 112411;ERK2 activation 111446;Activation of BIM and translocation to mitochondria hsa00970;Aminoacyl-tRNA biosynthesis - Homo sapiens (human) 174411;Polymerase switching on the C-strand of the telomere 110381;Resolution of AP sites via the single-nucleotide replacement pathway 75877;Conversion of Fatty Acyl-CoA to Phosphatidic Acid 163560;Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis hsa00052;Galactose metabolism - Homo sapiens (human) 210991;Basigin interactions 77387;Insulin receptor recycling 109703;PKB-mediated events 190322;FGFR4 ligand binding and activation 74259;Purine catabolism 70793;Leucine catabolism 73854;RNA Polymerase I Promoter Clearance 73937;Transcription-coupled NER (TC-NER) 69473;G2/M DNA damage checkpoint 71401;Oxidative decarboxylation of alpha-ketoglutarate to succinyl CoA by alpha-ketoglutarate dehydrogenase 191273;Cholesterol biosynthesis 165720;S6K1 signalling 75109;Triacylglyceride Biosynthesis 110330;Recognition and association of DNA glycosylase with site containing an affected purine hsa04610;Complement and coagulation cascades - Homo sapiens (human) 75892;Platelet Adhesion to exposed collagen 164516;Minus-strand DNA synthesis 157858;Gap junction trafficking and regulation 159418;Recycling of bile acids and salts 166016;Toll Like Receptor 4 (TLR4) Cascade hsa00030;Pentose phosphate pathway - Homo sapiens (human) 111452;Activation and oligomerization of BAK protein 142045;Alcohol Dehydrogenase hsa00510;N-Glycan biosynthesis - Homo sapiens (human) 71182;Phenylalanine and tyrosine catabolism 190377;FGFR2b ligand binding and activation 142033;Ethanol Catabolism 73885;Nucleotide Excision Repair 114666;G alpha Q cascade 110331;Cleavage of the damaged purine 70726;Oxidative decarboxylation of alpha-ketoisocaproate to isovaleryl-CoA by branched-chain alpha-ketoacid dehydrogenase 212718;EGFR interacts with phospholipase C-gamma 75067;Processing of Capped Intronless Pre-mRNA hsa04130;SNARE interactions in vesicular transport - Homo sapiens (human) 191345;Transformation of lanosterol to cholesterol 139943;PLC-mediated hydrolysis 188081;Toll Like Receptor 11 (TLR11) Cascade (Murine) 74967;Repair synthesis of patch ~27-30 bases long by DNA polymerase hsa00232;Caffeine metabolism - Homo sapiens (human) 167827;The proton buffering model hsa00051;Fructose and mannose metabolism - Homo sapiens (human) 111453;BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members 168138;Toll Like Receptor 9 (TLR9) Cascade 176974;Unwinding of DNA 71032;Propionyl-CoA catabolism 190372;FGFR3c ligand binding and activation 187577;SCF(Skp2)-mediated degradation of p27/p21 110357;Displacement of DNA glycosylase by APE1 198745;Signalling to STAT3 70221;Glycogen breakdown (glycogenolysis) 75148;ATM mediated phosphorylation of repair proteins 162658;Golgi Cisternae Pericentriolar Stack Reorganization 69298;Association of licensing factors with the pre-replicative complex 140181;Cytochrome p450 191647;c-src mediated regulation of Cx43 function and closure of gap junctions 70794;Oxidative decarboxylation of alpha-keto-beta-methylvalerate to alpha-methylbutyryl-CoA by branched-chain alpha-ketoacid dehydrogenase 73864;RNA Polymerase I Transcription 75894;Synthesis of lysophosphatidic acid from glycerol-3-phosphate # of genes 37 32 28 25 24 23 23 22 21 20 20 20 20 20 19 19 19 18 18 17 17 17 17 16 16 15 15 15 14 14 14 14 14 13 13 12 12 11 11 11 11 11 11 10 10 10 10 10 10 10 10 10 10 10 9 9 9 9 9 9 9 9 9 9 8 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 HUGO Symbol Name # of pathways 11179 SOD1 superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) 2 * * 1516 CAT catalase 8 * * * * * * * * 620 APP amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) 7 * * * * * * * 19986 CYCS cytochrome c, somatic 12 * * * * * * * * * * * * 7873 NOS2A nitric oxide synthase 2A (inducible, hepatocytes) 4 * * * * 11180 SOD2 superoxide dismutase 2, mitochondrial 0 990 BCL2 B-cell CLL/lymphoma 2 13 * * * * * * * * * * * * * 31395 COX8B cytochrome c oxidase, subunit 8B pseudogene 0 7872 NOS1 nitric oxide synthase 1 (neuronal) 4 * * * * 1504 CASP3 caspase 3, apoptosis-related cysteine peptidase 20 * * * * * * * * * * * * * * * * * * * * 7794 NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) 20 * * * * * * * * * * * * * * * * * * * * 11892 TNF tumor necrosis factor (TNF superfamily, member 2) 18 * * * * * * * * * * * * * * * * * * 10417 RPS27A ribosomal protein S27a 43 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 399 ALB albumin 9 * * * * * * * * * 10940 SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1 * 6871 MAPK1 mitogen-activated protein kinase 1 58 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 6893 MAPT microtubule-associated protein tau 3 * * * 118 ACO2 aconitase 2, mitochondrial 5 * * * * * 391 AKT1 v-akt murine thymoma viral oncogene homolog 1 41 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 11920 FAS Fas (TNF receptor superfamily, member 6) 12 * * * * * * * * * * * * 1613 CCS copper chaperone for superoxide dismutase 1 * 4571 GRIA1 glutamate receptor, ionotropic, AMPA 1 3 * * * 12805 XDH xanthine dehydrogenase 6 * * * * * * 727 ARTN artemin 0 5013 HMOX1 heme oxygenase (decycling) 1 1 * 1033 BDNF brain-derived neurotrophic factor 2 * * 613 APOE apolipoprotein E 3 * * * 7808 NGF nerve growth factor (beta polypeptide) 3 * * * 5232 HSPA1A heat shock 70kDa protein 1A 2 * * 3951 FXN frataxin 0 11998 TP53 tumor protein p53 24 * * * * * * * * * * * * * * * * * * * * * * * * 8768 AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1 * 3796 FOS v-fos FBJ murine osteosarcoma viral oncogene homolog 5 * * * * * 4235 GFAP glial fibrillary acidic protein 2 * * 6204 JUN jun oncogene 16 * * * * * * * * * * * * * * * * 1511 CASP9 caspase 9, apoptosis-related cysteine peptidase 22 * * * * * * * * * * * * * * * * * * * * * * 4623 GSR glutathione reductase 3 * * * 4141 GAPDH glyceraldehyde-3-phosphate dehydrogenase 12 * * * * * * * * * * * * 6876 MAPK14 mitogen-activated protein kinase 14 14 * * * * * * * * * * * * * * 12435 TXN thioredoxin 12 * * * * * * * * * * * * 14874 NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0 11138 SNCA synuclein, alpha (non A4 component of amyloid precursor) 3 * * * 7876 NOS3 nitric oxide synthase 3 (endothelial cell) 6 * * * * * * 1499 CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 3 * * * 1991 CKB creatine kinase, brain 2 * * 9393 PRKCA protein kinase C, alpha 25 * * * * * * * * * * * * * * * * * * * * * * * * * 9508 PSEN1 presenilin 1 (Alzheimer disease 3) 6 * * * * * * 12680 VEGFA vascular endothelial growth factor A 16 * * * * * * * * * * * * * * * * 5992 IL1B interleukin 1, beta 7 * * * * * * * 1912 CHAT choline acetyltransferase 1 * 2244 COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 1 * 4341 GLUL glutamate-ammonia ligase (glutamine synthetase) 5 * * * * * 4572 GRIA2 glutamate receptor, ionotropic, AMPA 2 3 * * * 2295 CP ceruloplasmin (ferroxidase) 1 * 25806 GSTCD glutathione S-transferase, C-terminal domain containing 0 4827 HBB hemoglobin, beta 0 14133 SEPX1 selenoprotein X, 1 0 4553 GPX1 glutathione peroxidase 1 3 * * * 5464 IGF1 insulin-like growth factor 1 (somatomedin C) 12 * * * * * * * * * * * * 576 APAF1 apoptotic peptidase activating factor 1 9 * * * * * * * * * 2294 COX8A cytochrome c oxidase subunit 8A (ubiquitous) 2 * * 6877 MAPK3 mitogen-activated protein kinase 3 58 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 6881 MAPK8 mitogen-activated protein kinase 8 23 * * * * * * * * * * * * * * * * * * * * * * * 9509 PSEN2 presenilin 2 (Alzheimer disease 4) 5 * * * * * 11936 FASLG Fas ligand (TNF superfamily, member 6) 11 * * * * * * * * * * * 10990 SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 9 * * * * * * * * * 11919 CD40 CD40 molecule, TNF receptor superfamily member 5 5 * * * * * 26515 COQ10A coenzyme Q10 homolog A (S. cerevisiae) 0 17169 PRDX4 peroxiredoxin 4 0 11740 TF transferrin 0 412 ALDH9A1 aldehyde dehydrogenase 9 family, member A1 16 * * * * * * * * * * * * * * * * 992 BCL2L1 BCL2-like 1 8 * * * * * * * * 2898 DLD dihydrolipoamide dehydrogenase 22 * * * * * * * * * * * * * * * * * * * * * * 4624 GSS glutathione synthetase 6 * * * * * * 16554 SLC25A6P1 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6, pseudogene 1 0 4638 GSTP1 glutathione S-transferase pi 4 * * * * 4851 HTT huntingtin 2 * * 5438 IFNG interferon, gamma 7 * * * * * * * 11782 TH tyrosine hydroxylase 2 * * 9353 PRDX2 peroxiredoxin 2 0 14374 NLRP1 NLR family, pyrin domain containing 1 0 2578 CYBB cytochrome b-245, beta polypeptide (chronic granulomatous disease) 1 * 7782 NFE2L2 nuclear factor (erythroid-derived 2)-like 2 1 * 4232 GDNF glial cell derived neurotrophic factor 0 5014 HMOX2 heme oxygenase (decycling) 2 1 * 1784 CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 30 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 10941 SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0 7661 NCF2 neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2) 1 * 9605 PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 6 * * * * * * 14929 SIRT1 sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) 2 * * 17772 TXN2 thioredoxin 2 0 20374 GSX1 GS homeobox 1 0 4057 G6PD glucose-6-phosphate dehydrogenase 5 * * * * * 5261 HSPD1 heat shock 60kDa protein 1 (chaperonin) 2 * * 11506 SYP synaptophysin 0 381 AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 5 * * * * * 18985 DCXR dicarbonyl/L-xylulose reductase 1 * 7739 NEFL neurofilament, light polypeptide 68kDa 1 * 16753 PRDX6 peroxiredoxin 6 13 * * * * * * * * * * * * 9391 PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 5 * * * * * 4092 GAD1 glutamate decarboxylase 1 (brain, 67kDa) 6 * * * * * * 6886 MAPK9 mitogen-activated protein kinase 9 13 * * * * * * * * * * * * * 7889 NOX1 NADPH oxidase 1 1 * 1706 CD8A CD8a molecule 6 * * * * * * 670 RHOD ras homolog gene family, member D 3 * * * 795 ATM ataxia telangiectasia mutated 17 * * * * * * * * * * * * * * * * * 2345 CREB1 cAMP responsive element binding protein 1 9 * * * * * * * * * 2422 CS citrate synthase 4 * * * * 2903 DLG4 discs, large homolog 4 (Drosophila) 0 4817 HARS2 histidyl-tRNA synthetase 2, mitochondrial (putative) 2 * * 5241 HSPA8 heat shock 70kDa protein 8 2 * * 5244 HSPA9 heat shock 70kDa protein 9 (mortalin) 0 5247 HSPB2 heat shock 27kDa protein 2 0 6081 INS insulin 17 * * * * * * * * * * * * * * * * * 6782 MAFK v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) 0 7897 NPC1 Niemann-Pick disease, type C1 0 9704 PVALB parvalbumin 0 443 ALS2 amyotrophic lateral sclerosis 2 (juvenile) 2 * * 2197 COL1A1 collagen, type I, alpha 1 14 * * * * * * * * * * * * * * 21528 DIABLO diablo homolog (Drosophila) 7 * * * * * * * 4646 GTF2A1 general transcription factor IIA, 1, 19/37kDa 4 * * * * 5269 HSPE1 heat shock 10kDa protein 1 (chaperonin 10) 0 6879 MAPK6 mitogen-activated protein kinase 6 0 8023 NTF3 neurotrophin 3 4 * * * * 8975 PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide 44 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 10451 RRM1 ribonucleotide reductase M1 16 * * * * * * * * * * * * * * * * 1546 SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0 798 ATOX1 ATX1 antioxidant protein 1 homolog (yeast) 0 949 BAK1 BCL2-antagonist/killer 1 3 * * * 3229 EGF epidermal growth factor (beta-urogastrone) 15 * * * * * * * * * * * * * * * 3346 ENDOG endonuclease G 1 * 5991 IL1A interleukin 1, alpha 5 * * * * * 7553 MYC v-myc myelocytomatosis viral oncogene homolog (avian) 12 * * * * * * * * * * * * 7711 NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 2 * * 14537 NPC2 Niemann-Pick disease, type C2 0 15917 PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 18 * * * * * * * * * * * * * * * * * * 9352 PRDX1 peroxiredoxin 1 0 21148 RNF123 ring finger protein 123 0 11049 SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0 12468 UBC ubiquitin C 1 * 12791 WRN Werner syndrome 0 3435 ERCC3 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) 7 * * * * * * * 11917 TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2 * * 3711 FKBP1A FK506 binding protein 1A, 12kDa 1 * 8978 PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide 28 * * * * * * * * * * * * * * * * * * * * * * * * * * * * 12513 UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2 * * 587 APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1 * 9253 PPIA peptidylprolyl isomerase A (cyclophilin A) 15 * * * * * * * * * * * * * * * 7965 NR1H2 nuclear receptor subfamily 1, group H, member 2 0 12022 TPT1 tumor protein, translationally-controlled 1 0 1325 C4BPA complement component 4 binding protein, alpha 1 * 9801 RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 30 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 1509 CASP8 caspase 8, apoptosis-related cysteine peptidase 16 * * * * * * * * * * * * * * * * 3573 FADD Fas (TNFRSF6)-associated via death domain 10 * * * * * * * * * * 10945 SLC1A7 solute carrier family 1 (glutamate transporter), member 7 0 10939 SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0 11121 SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 1 * 2728 DDOST dolichyl-diphosphooligosaccharide-protein glycosyltransferase 2 * * 4311 GCLC glutamate-cysteine ligase, catalytic subunit 3 * * * 270 PARP1 poly (ADP-ribose) polymerase family, member 1 0 1062 BLVRA biliverdin reductase A 1 * 7211 MPG N-methylpurine-DNA glycosylase 1 * 9237 PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 2 * * 9816 RAD50 RAD50 homolog (S. cerevisiae) 7 * * * * * * * 10840 SHC1 SHC (Src homology 2 domain containing) transforming protein 1 11 * * * * * * * * * * * 2859 DHCR24 24-dehydrocholesterol reductase 5 * * * * * 4312 GCLM glutamate-cysteine ligase, modifier subunit 3 * * * 7230 MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 7 * * * * * * * 7660 NCF1 neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) 1 * 10944 SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0 1058 BLM Bloom syndrome 0 3650 FEN1 flap structure-specific endonuclease 1 18 * * * * * * * * * * * * * * * * * * 7427 MT-CYB mitochondrially encoded cytochrome b 0 22948 NLRP2 NLR family, pyrin domain containing 2 0 11427 STUB1 STIP1 homology and U-box containing protein 1 1 * 249 ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 14 * * * * * * * * * * * * * * 20473 BRIP1 BRCA1 interacting protein C-terminal helicase 1 0 3769 FMO1 flavin containing monooxygenase 1 22 * * * * * * * * * * * * * * * * * * * * * * 6833 MAOA monoamine oxidase A 10 * * * * * * * * * * 7714 NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 2 * * 8784 PDE5A phosphodiesterase 5A, cGMP-specific 2 * * 9411 PRKCSH protein kinase C substrate 80K-H 0 9817 RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 8 * * * * * * * * 10886 SIRT2 sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) 2 * * 23696 TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0 4055 XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) 9 * * * * * * * * * 132 ACTB actin, beta 8 * * * * * * * * 2577 CYBA cytochrome b-245, alpha polypeptide 1 * 2928 DMD dystrophin (muscular dystrophy, Duchenne and Becker types) 0 6018 IL6 interleukin 6 (interferon, beta 2) 5 * * * * * 6776 MAF v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) 0 6840 MAP2K1 mitogen-activated protein kinase kinase 1 45 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 8024 NTF4 neurotrophin 4 1 * 8979 PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 43 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 9413 PRKDC protein kinase, DNA-activated, catalytic polypeptide 5 * * * * * 12950 SF1 splicing factor 1 0 11655 TCP1 t-complex 1 18 * * * * * * * * * * * * * * * * * * 61 ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1 * 959 BAX BCL2-associated X protein 9 * * * * * * * * * 3013 DPYS dihydropyrimidinase 6 * * * * * * 16731 FBXO32 F-box protein 32 0 6817 MAL mal, T-cell differentiation protein 5 * * * * * 6834 MAOB monoamine oxidase B 10 * * * * * * * * * * 7662 NCF4 neutrophil cytosolic factor 4, 40kDa 1 * 8031 NTRK1 neurotrophic tyrosine kinase, receptor, type 1 18 * * * * * * * * * * * * * * * * * * 8729 PCNA proliferating cell nuclear antigen 25 * * * * * * * * * * * * * * * * * * * * * * * * * 14180 PDIA2 protein disulfide isomerase family A, member 2 0 14581 PINK1 PTEN induced putative kinase 1 2 * * 9257 PPID peptidylprolyl isomerase D (cyclophilin D) 1 * 16860 SART3 squamous cell carcinoma antigen recognized by T cells 3 0 14931 SIRT3 sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) 0 12814 XPA xeroderma pigmentosum, complementation group A 1 * 48 ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 1 * 333 AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1 * 429 ALOX12 arachidonate 12-lipoxygenase 5 * * * * * 1515 CAST calpastatin 0 2773 DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 4 * * * * 2983 DNTT deoxynucleotidyltransferase, terminal 1 * 13273 DUOX2 dual oxidase 2 0 3189 EEF1A1 eukaryotic translation elongation factor 1 alpha 1 4 * * * * 4250 GGT1 gamma-glutamyltransferase 1 5 * * * * * 4330 GLRX glutaredoxin (thioltransferase) 4 * * * * 24959 GSX2 GS homeobox 2 0 5238 HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 3 * * * 5465 IGF1R insulin-like growth factor 1 receptor 7 * * * * * * * 6115 IREB2 iron-responsive element binding protein 2 0 6206 JUND jun D proto-oncogene 1 * 23177 KEAP1 kelch-like ECH-associated protein 1 1 * 7545 MYB v-myb myeloblastosis viral oncogene homolog (avian) 0 7715 NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 2 * * 7737 NEFH neurofilament, heavy polypeptide 200kDa 2 * * 7734 NEFM neurofilament, medium polypeptide 150kDa 1 * 7804 NFYA nuclear transcription factor Y, alpha 1 * 7891 NOX4 NADPH oxidase 4 0 2874 NQO1 NAD(P)H dehydrogenase, quinone 1 1 * 8032 NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4 * * * * 8125 OGG1 8-oxoguanine DNA glycosylase 12 * * * * * * * * * * * * 8806 PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 9 * * * * * * * * * 8808 PDHB pyruvate dehydrogenase (lipoamide) beta 9 * * * * * * * * * 9208 POR P450 (cytochrome) oxidoreductase 0 9577 PSPH phosphoserine phosphatase 1 * 9824 RAD52 RAD52 homolog (S. cerevisiae) 7 * * * * * * * 9827 RAD9A RAD9 homolog A (S. pombe) 3 * * * 10436 RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 15 * * * * * * * * * * * * * * * 11007 SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 3 * * * 11014 SLC30A3 solute carrier family 30 (zinc transporter), member 3 0 11181 SOD3 superoxide dismutase 3, extracellular 0 11742 TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0 12008 TPH1 tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) 1 * 1158 TSPO translocator protein (18kDa) 1 * 12442 TYR tyrosinase (oculocutaneous albinism IA) 4 * * * * 12609 USP11 ubiquitin specific peptidase 11 0 34 ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1 * 80 ABP1 amiloride binding protein 1 (amine oxidase (copper-containing)) 8 * * * * * * * * 15814 ACSS2 acyl-CoA synthetase short-chain family member 2 7 * * * * * * * 21285 ADCY10 adenylate cyclase 10 (soluble) 1 * 380 AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 14 * * * * * * * * * * * * * * 437 ALPI alkaline phosphatase, intestinal 2 * * 25361 ARHGAP24 Rho GTPase activating protein 24 2 * * 784 ATF2 activating transcription factor 2 6 * * * * * * 30213 ATP13A2 ATPase type 13A2 2 * * 841 ATP5G1 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9) 6 * * * * * * 13509 AVEN apoptosis, caspase activation inhibitor 0 14078 BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0 936 BAD BCL2-antagonist of cell death 17 * * * * * * * * * * * * * * * * * 939 BAG3 BCL2-associated athanogene 3 0 30000 BBS9 Bardet-Biedl syndrome 9 0 1101 BRCA2 breast cancer 2, early onset 9 * * * * * * * * * 1260 C21orf2 chromosome 21 open reading frame 2 0 1317 C2orf3 chromosome 2 open reading frame 3 0 13716 C4orf6 chromosome 4 open reading frame 6 0 1442 CALM1 calmodulin 1 (phosphorylase kinase, delta) 17 * * * * * * * * * * * * * * * * * 24190 CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0 16014 CASD1 CAS1 domain containing 1 0 1503 CASP2 caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) 0 25079 CCDC34 coiled-coil domain containing 34 0 1618 CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0 1678 CD4 CD4 molecule 19 * * * * * * * * * * * * * * * * * * * 1682 CD47 CD47 molecule 4 * * * * 1693 CD68 CD68 molecule 0 1773 CDK4 cyclin-dependent kinase 4 17 * * * * * * * * * * * * * * * * * 1848 CEL carboxyl ester lipase (bile salt-stimulated lipase) 4 * * * * 2169 CNTF ciliary neurotrophic factor 2 * * 2206 COL4A4 collagen, type IV, alpha 4 4 * * * * 2264 COX17 COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) 1 * 2355 CRH corticotropin releasing hormone 2 * * 12024 CRISP2 cysteine-rich secretory protein 2 0 2432 CSF1 colony stimulating factor 1 (macrophage) 2 * * 17937 CUZD1 CUB and zona pellucida-like domains 1 0 2579 CYC1 cytochrome c-1 2 * * 2615 CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 2 * * 13748 DLEU2 deleted in lymphocytic leukemia, 2 0 3062 DUOX1 dual oxidase 1 0 3415 EPO erythropoietin 3 * * * 3493 ETV4 ets variant gene 4 (E1A enhancer binding protein, E1AF) 0 3665 FGF1 fibroblast growth factor 1 (acidic) 15 * * * * * * * * * * * * * * * 3701 FHIT fragile histidine triad gene 3 * * * 3763 FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 6 * * * * * * 3768 FMN1 formin 1 0 4323 GLO1 glyoxalase I 1 * 4331 GLS glutaminase 5 * * * * * 16769 GORASP1 golgi reassembly stacking protein 1, 65kDa 4 * * * * 4455 GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 6 * * * * * * 4556 GPX4 glutathione peroxidase 4 (phospholipid hydroperoxidase) 2 * * 4605 GRP gastrin-releasing peptide 1 * 4739 H2AFX H2A histone family, member X 2 * * 4805 HAGH hydroxyacylglutathione hydrolase 1 * 4983 HMGB1 high-mobility group box 1 0 5173 HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 32 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 5253 HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 5 * * * * * 5385 IDH3B isocitrate dehydrogenase 3 (NAD+) beta 3 * * * 5472 IGFBP3 insulin-like growth factor binding protein 3 1 * 5962 IL10 interleukin 10 3 * * * 6001 IL2 interleukin 2 4 * * * * 6014 IL4 interleukin 4 5 * * * * * 6207 JUP junction plakoglobin 1 * 6307 KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 7 * * * * * * * 25888 KLHL22 kelch-like 22 (Drosophila) 0 6563 LGALS3 lectin, galactoside-binding, soluble, 3 0 6780 MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 0 6781 MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0 6843 MAP2K3 mitogen-activated protein kinase kinase 3 4 * * * * 6848 MAP3K1 mitogen-activated protein kinase kinase kinase 1 16 * * * * * * * * * * * * * * * * 6915 MB myoglobin 0 7097 MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 2 * * 7212 MPHOSPH1 M-phase phosphoprotein 1 0 7377 MSRA methionine sulfoxide reductase A 0 7414 MT-ATP6 mitochondrially encoded ATP synthase 6 0 7415 MT-ATP8 mitochondrially encoded ATP synthase 8 0 7419 MT-CO1 mitochondrially encoded cytochrome c oxidase I 0 7455 MT-ND1 mitochondrially encoded NADH dehydrogenase 1 0 7456 MT-ND2 mitochondrially encoded NADH dehydrogenase 2 0 7458 MT-ND3 mitochondrially encoded NADH dehydrogenase 3 0 7459 MT-ND4 mitochondrially encoded NADH dehydrogenase 4 0 7460 MT-ND4L mitochondrially encoded NADH dehydrogenase 4L 0 7461 MT-ND5 mitochondrially encoded NADH dehydrogenase 5 0 7462 MT-ND6 mitochondrially encoded NADH dehydrogenase 6 0 7473 MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2 * * 23212 MYH14 myosin, heavy chain 14 2 * * 7577 MYH7 myosin, heavy chain 7, cardiac muscle, beta 1 * 7688 NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 2 * * 7707 NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2 * * 7797 NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 17 * * * * * * * * * * * * * * * * * 19374 NKRF NFKB repressing factor 0 16400 NLRP3 NLR family, pyrin domain containing 3 0 7896 NPAT nuclear protein, ataxia-telangiectasia locus 0 7983 NR5A1 nuclear receptor subfamily 5, group A, member 1 0 8548 P4HB procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide 3 * * * 8607 PARK2 Parkinson disease (autosomal recessive, juvenile) 2, parkin 3 * * * 8988 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0 9065 PLCG1 phospholipase C, gamma 1 24 * * * * * * * * * * * * * * * * * * * * * * * * 9122 PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0 9175 POLD1 polymerase (DNA directed), delta 1, catalytic subunit 125kDa 7 * * * * * * * 9201 POMC proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin) 3 * * * 9308 PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 1 * 9354 PRDX3 peroxiredoxin 3 0 9380 PRKACA protein kinase, cAMP-dependent, catalytic, alpha 18 * * * * * * * * * * * * * * * * * * 9388 PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) 5 * * * * * 17348 PRPF3 PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) 0 9461 PRPH peripherin 1 * 9567 PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 5 * * * * * 9588 PTEN phosphatase and tensin homolog (mutated in multiple advanced cancers 1) 17 * * * * * * * * * * * * * * * * * 9655 PTPN3 protein tyrosine phosphatase, non-receptor type 3 0 9717 PXMP3 peroxisomal membrane protein 3, 35kDa (Zellweger syndrome) 0 9752 QDPR quinoid dihydropteridine reductase 3 * * * 9948 RECQL RecQ protein-like (DNA helicase Q1-like) 0 9950 RECQL5 RecQ protein-like 5 0 10289 RPA1 replication protein A1, 70kDa 5 * * * * * 445 SETX senataxin 9 * * * * * * * * * 10780 SFRS1 splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) 23 * * * * * * * * * * * * * * * * * * * * * * * 10876 SIGLEC7 sialic acid binding Ig-like lectin 7 0 24624 SIL1 SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae) 0 10963 SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0 17128 SLC39A3 solute carrier family 39 (zinc transporter), member 3 0 11205 SP1 Sp1 transcription factor 1 * 11240 SPHK1 sphingosine kinase 1 8 * * * * * * * * 11283 SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 26 * * * * * * * * * * * * * * * * * * * * * * * * * * 26333 SRFBP1 serum response factor binding protein 1 0 11517 TAC1 tachykinin, precursor 1 1 * 11609 TBXAS1 thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) 5 * * * * * 19737 TENC1 tensin like C1 domain containing phosphatase (tensin 2) 0 11729 TERF2 telomeric repeat binding factor 2 2 * * 11763 TFRC transferrin receptor (p90, CD71) 1 * 21354 TICAM2 toll-like receptor adaptor molecule 2 2 * * 12015 TPO thyroid peroxidase 7 * * * * * * * 12343 TRNAR1 transfer RNA arginine 1 (anticodon UCU) 0 12716 TRPV1 transient receptor potential cation channel, subfamily V, member 1 1 * 12405 TTR transthyretin (prealbumin, amyloidosis type I) 0 12408 TUBA3C tubulin, alpha 3c 3 * * * 20778 TUBB tubulin, beta 3 * * * 12420 TUFM Tu translation elongation factor, mitochondrial 0 29884 UBASH3B ubiquitin associated and SH3 domain containing, B 0 17598 UBE2J1 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) 2 * * 12517 UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 4 * * * * 30862 UQCR ubiquinol-cytochrome c reductase, 6.4kDa subunit 2 * * 12642 VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 4 * * * * 12649 VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 1 * 12780 WNT2 wingless-type MMTV integration site family member 2 4 * * * * 592 XIAP X-linked inhibitor of apoptosis 4 * * * *