RESEARCH TOPICS

Here are the projects that I am currently working on here at the University of North Dakota. Details are to come shortly.

Literature Mining

SciMiner - Bio-NLP (Natural Language Processing) web-application for finding molecular target (gene/protein) in biomedical literatures and functionaly enrichment analyses (Gene, GO, MeSH, Pathway, and PPI).

SciMiner-VO - Expansion of SciMiner to include the functionality of identifying Vaccine Ontology (VO) terms and indexing PubMed documents with VOs.

Systems Pharmacology

Development of a drug-repurposing prioritization system based on high-throughput gene expression/drug perturbation data.

Bioinformatics Approaches to Human Diseases

Diabetic Peripheral Neuropathy (DPN): identification of conserved/unique genetic/transcriptomic signatures and the underlying mechanisms of DPN.
Epileptogenesis: identification of potential therapeutic targets of epileptogenesis conserved/unique genetic/transcriptomic signatures and the underlying mechanisms of DPN.
Neurological disorders: identification of pathogenic mechanisms of multiple neurological disorders (such as Alzheimer's, Parkinson, Lou Gehrig's disease) using systems biology approaches combining multiple Omics-spaces.