HUGO ID Detailed Result 9600

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
17574754	prostaglandin receptor	prostaglandin receptor	1.0	recent studies investigating the functions of selected prostaglandin receptor pathways in mediating cox 2 neurotoxicity have demonstrated both toxic and paradoxically neuroprotective effects of several receptors in models of excitotoxicity.
17574754	prostaglandin receptor	prostaglandin receptor	1.0	cox 2 neurotoxicity is presumed to be mediated by one or more of these prostaglandin receptor signaling cascades.
17574754	prostaglandin receptor	prostaglandin receptor	1.0	recent studies using genetic models have begun to shed light on the function of prostaglandin receptor signaling in models of neuronal damage.
17574754	prostaglandin receptor	prostaglandin receptor	1.0	these divergent effects of prostaglandin receptor signaling on neuronal survival occur in models of excitotoxicity where neuronal injury occurs in large part from overactivation of glutamate ionotropic receptors and downstream disruptions in intrace
17574754	prostaglandin receptor	prostaglandin receptor	1.0	prostaglandin receptor agonists were prepared as a 10 mm stock in 100% ethanol and frozen at _amp_#x2212;70 _amp_#xb0;c until use.
17574754	prostaglandin receptor	prostaglandin receptor	1.0	slices were then stimulated with 10 _amp_#x3bc;m nmda for 1 h in the presence of prostaglandin receptor agonists or vehicle; after stimulation media was replaced with fresh media containing either receptor agonist or vehicle ethanol _amp_#x2264;0.1% and pi 5 _amp_#x3bc;g/ml for 23 h.
17574754	prostaglandin receptor	prostaglandin receptor	1.0	taken together these data indicate that additional prostaglandin receptor signaling cascades exert significant neuroprotective effects in excitoxicity.
17574754	prostaglandin receptor	prostaglandin receptor	1.0	in this study we identify additional prostaglandin receptor signaling pathways that rescue neurons in two organotypic models of excitotoxic neuronal injury.
17574754	prostaglandin receptor	prostaglandin receptor	1.0	in a second model using hippocampal slices we have identified three additional prostaglandin receptor signaling pathways that confer neuroprotection in the setting of nmda toxicity.
17574754	prostaglandin receptor	prostaglandin receptor	1.0	the increased toxicity of lps with addition of ep2/ep3 receptor agonists is relevant to recent in vivo studies demonstrating that in the setting of inflammation prostaglandin receptor signaling can exhibit an opposite and toxic effect on neurons.
17901552	prostaglandin receptor	prostaglandin receptor	1.0	umed be due to downstream effects of one or more prostaglandin products including pge2 pgd2 pgf2alpha pgi2 prostacylin and txa2 thromboxane that effect cellular changes through activation of specific prostaglandin receptor subtypes and second messenger systems.