HUGO ID Detailed Result 9545


HUGO ID 9545
Symbol PSMB8
Name proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
#Occurrence 16
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
17008387LMP7LMP72.3to manufacturer's instructions and immunostained using rabbit polyclonal anti-proteasome 20S LMP7 (dilution dilution 1 1000 Abcam Cambridge UK rabbit polyclonal anti-proteasome 
17008387LMP7LMP72.3beta1 beta2 and beta5 have close homologs LMP2 MECL-1 and LMP7 that are selectively induced under certain conditions such as the 
17008387LMP7LMP72.3The levels of immunoproteasome (LMP7) LMP7 increased along with the disease progression in the spinal cord 
17008387LMP7LMP72.3In G93A-SOD1 TG rats the levels of 20S LMP7 protein in the spinal cord was increased 6-fold between 8 
17008387LMP7LMP72.3PDTC treatment completely prevented the induction of 20S LMP7 at the end stage of G93A-SOD1 TG rats (A A 
17008387LMP7LMP72.3A it is noteworthy that in WT animals 20S LMP7 was barely detectable or undetectable in the cytosolic fraction and 
17008387LMP7LMP72.3Fig 6 20S X and 20S LMP7 expression in lumbar spinal cord 
17008387LMP7LMP72.3B 20S LMP7 an inducible beta-subunit of immunoproteasome was expressed only in the 
17008387LMP7LMP72.3B immunoproteasome 20S LMP7 was expressed mainly in astrocytes and microglia 
17008387LMP7LMP72.3cord were used for immunohistochemistry with rabbit polyclonal anti-proteasome 20S LMP7 (dilution dilution 1 500 Abcam or rabbit polyclonal anti-proteasome 20S 
17008387LMP7LMP72.3spinal cord we used immunoblotting for 20S X and 20S LMP7 markers of constitutive and inducible proteasome respectively 
17008387LMP7LMP72.3Instead the expression of immunoproteasome measured by immunoblotting for 20S LMP7 an inducible beta subunit was strongly increased in the spinal 
17008387LMP7LMP72.3The amount of LMP7 protein was increased 6-fold between 8 and 16 weeks of 
17008387LMP7LMP72.3PDTC treatment completely prevented the induction of 20S LMP7 at the end stage of G93A-SOD1 TG rats (1476 1476 
17008387LMP7LMP72.3It is noteworthy that in WT animals 20S LMP7 was barely detectable or undetectable in the cytosolic fraction ( 
17008387LMP7LMP72.3Double-labeling immunohistochemistry with confocal imaging showed that the immunoproteasome 20S LMP7 was expressed in astrocytes and microglia ( Fig 7B whereas