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| 10525172 | NF-L | NF-L | 1.3 | These investigators also showed that the motor neuron protein neurofilament- NF-L could bind zinc atoms with sufficient affinity to potentially remove | |  |
| 10525172 | NF-L | NF-L | 1.3 | no significant qualitative or quantitative modifications in the nitrotyrosine-immunoreactivity of NF-L isolated from sporadic ALS cervical spinal cord tissue as compared | | |
| 17015226 | NF-L | NF-L | 2.4 | In addition mice with increased levels of wild-type NF-H or NF-L subunits develop age-dependent motor neuron pathology ( Cote et_amp_#xa0 al. | | |
| 17015226 | NF-L | NF-L | 2.4 | et_amp_#xa0 al. 1993 while expression of a point mutation in NF-L at levels corresponding to that expected for dominantly inherited disease | | |
| 17015226 | NF-L | NF-L | 2.4 | ( Garcia et_amp_#xa0 al. 2006 although dominant point mutations in NF-L have been linked to a milder motor neuron disease Charcot-Marie-Tooth | | |
| 17015226 | NF-L | NF-L | 2.4 | wobbler and transgenic mice expressing a point mutation in the NF-L gene ( Coulpier et_amp_#xa0 al. 1996 and Houseweart and Cleveland | | |
| 17015226 | NF-L | NF-L | 2.4 | Neurofilaments are obligate heteropolymers of NF light (NF-L), NF-L NF medium (NF-M), NF-M and NF heavy (NF-H) NF-H subunits | | |
| 17015226 | NF-L | NF-L | 2.4 | subunits and interestingly transgenic mice expressing a point mutation in NF-L develop motor neuron disease ( Lee et_amp_#xa0 al. 1994 | | |
| 17015226 | NF-L | NF-L | 2.4 | Removal of all axonal neurofilaments by deletion of NF-L substantially prolonged survival of hSOD1 G85R and hSOD1 G37R mice | | |
| 10525172 | nf l | nf l | 1.0 | these investigators also showed that the motor neuron protein neurofilament nf l could bind zinc atoms with sufficient affinity to potentially remove zinc from sod and that the loss of zinc from wild type sod almost doubled the efficiency of this enzyme for catalyzing for peroxyn | | |
| 10525172 | nf l | nf l | 1.0 | however strong et al. [ 81 ] recently reported that there were no significant qualitative or quantitative modifications in the nitrotyrosine immunoreactivity of nf l isolated from sporadic als cervical spinal cord tissue as compared with age matched non als controls. | | |
| 11173059 | neurofilament light | neurofilament light | 1.0 | moreover transgenic mice expressing increased quantities of neurofilament light or heavy subunits develop motor neuron pathology cote and xu . | | |
| 17015226 | nf l | nf l | 1.0 | in addition mice with increased levels of wild type nf h or nf l subunits develop age dependent motor neuron pathology cote et_amp_#xa0;al. 1993 and xu et_amp_#xa0;al. 1993 while expression of a point mutation in nf l at levels corresponding to that expected for d | | |
| 17015226 | nf l | nf l | 1.0 | subunits develop age dependent motor neuron pathology cote et_amp_#xa0;al. 1993 and xu et_amp_#xa0;al. 1993 while expression of a point mutation in nf l at levels corresponding to that expected for dominantly inherited disease produces fatal progressive paralysis lee et_amp_#xa0;al. 1994 . | | |
| 17015226 | nf l | nf l | 1.0 | ations in the three neurofilament genes in patient dnas failed to yield conclusive linkage to either sporadic or familial als patients garcia et_amp_#xa0;al. 2006 although dominant point mutations in nf l have been linked to a milder motor neuron disease charcot marie tooth cmt disease de jonghe et_amp_#xa0;al. 2001 and jordanova et_amp_#xa0;al. 2003 . | | |
| 17015226 | nf l | nf l | 1.0 | bcl 2 is unable to similarly rescue motor neuron death in other models such as wobbler and transgenic mice expressing a point mutation in the nf l gene coulpier et_amp_#xa0;al. 1996 and houseweart and cleveland 1999 . | | |
| 17015226 | nf l | nf l | 1.0 | neurofilaments are obligate heteropolymers of nf light nf l nf medium nf m and nf heavy nf h subunits and interestingly transgenic mice expressing a point mutation in nf l develop motor neuron disease lee et_amp_#xa0;al. 1994 . | | |
| 17015226 | nf l | nf l | 1.0 | removal of all axonal neurofilaments by deletion of nf l substantially prolonged survival of hsod1 g85r and hsod1 g37r mice nguyen et_amp_#xa0;al. 2001 and williamson et_amp_#xa0;al. 1998 as did removal of most axonal neurofilaments by excessive levels of | | |