HUGO ID Detailed Result 7737


HUGO ID 7737
Symbol NEFH
Name neurofilament, heavy polypeptide 200kDa
#Occurrence 8
#Paper 2

 


PMID Match String Actual String Score Flanking text Edited by Edit
14556941NFHNF-H0.3cords of MOG-treated mice showed an increase of abnormal dephosphorylated NF-H ( Fig 2G while minimal abnormal dephosphorylation was observed in 
14556941NFHNF-H0.3demonstrated axonal disruption indicating a large increase of abnormally dephosphorylated NF-H in MOG-immunized spinal cords in the riluzole-treated mice there was 
17015226NFHNF-H0.9In addition mice with increased levels of wild-type NF-H or NF-L subunits develop age-dependent motor neuron pathology ( Cote 
17015226NFHNF-H0.9or 45 KSP repeats in the tail domain of the NF-H subunit have been reported in 1% of sporadic ALS patients 
17015226NFHNF-H0.9(NF-L), NF-L NF medium (NF-M), NF-M and NF heavy (NF-H) NF-H subunits and interestingly transgenic mice expressing a point mutation in 
17015226NFHNF-H0.9did removal of most axonal neurofilaments by excessive levels of NF-H ( Couillard-Despres et_amp_#xa0 al. 1998 Kong and Xu 2000 and 
17015226NFHNF-H0.9to remove the phosphorylated _amp_#x201c tail_amp_#x201d domains of NF-M and NF-H that normally provide intra-axonal crosslinking of adjacent filaments 
17015226NFHNF-H0.9after elimination of the tail domains of the NF-M and NF-H subunits Lobsiger et_amp_#xa0 al. 2005 provide extended survival of SOD1