HUGO ID Detailed Result 270


HUGO ID 270
Symbol PARP1
Name poly (ADP-ribose) polymerase family, member 1
#Occurrence 12
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
18436268PARPPARP1.9levels of cleaved caspase-3 and poly(ADP-ribose)polymerase poly ADP-ribose polymerase (PARP) PARP but up-regulated the level of anti-apoptotic protein Bcl-2 
18436268PARPPARP1.9Cruz cleaved caspase-3 (1:1000, 1 1000 Cell signaling MA USA PARP and cleavage (1:1000, 1 1000 Cell signaling MA USA respectively 
18436268PARPPARP1.9we determined the protein level of Bcl-2 cleaved caspase-3 and PARP in the spinal cord after FA B12 or FA B12 
18436268PARPPARP1.9Bcl-2 and reduce the level of cleaved caspase-3 and cleaved PARP ( Fig._amp_#xa0 5 B 
18436268PARPPARP1.9by increasing Bcl-2 expression and inhibiting cleaved caspase-3 and cleaved PARP 
18436268PARPPARP1.9several important proteins such as Bcl-2 cleaved caspase-3 and cleaved PARP ( Baydas et_amp_#xa0 al. 2005 and Kruman et_amp_#xa0 al. 2000 
18436268PARPPARP1.9Cleaved caspase-3 and cleaved PARP represent the downstream signals of apoptosis which may contribute to 
18436268PARPPARP1.9expression of apoptosis-related proteins such as cleaved caspase-3 and cleaved PARP 
18436268PARPPARP1.9can significantly inhibit the levels of cleaved caspase-3 and cleaved PARP as well as up-regulate the levels of Bcl-2 
18436268PARPPARP1.9(B) B Western blot of Bcl-2 cleaved caspase-3 and cleaved PARP from spinal cord samples 
18436268PARPPARP1.9the expression of iNOS TNF-_amp_#x3b1 Bcl-2 cleaved caspase-3 and cleaved PARP in five groups 
18436268poly (adp-ribose) polymerasepoly adp ribose polymerase1.0moreover fa or fa + b12 treatment decreased the levels of cleaved caspase 3 and poly adp ribose polymerase parp but up regulated the level of anti apoptotic protein bcl 2.