HUGO ID Detailed Result 21683


HUGO ID 21683
Symbol NAPEPLD
Name N-acyl phosphatidylethanolamine phospholipase D
#Occurrence 10
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
17350694NAPE-PLDNAPE-PLD1.3been for N -acylphosphatidylethanolamine (NAPE)-specific NAPE -specific phospholipase D (NAPE-PLD) NAPE-PLD 59 and FAAH 60 and 61 with respect to AEA 
17350694NAPE-PLDNAPE-PLD1.3on its synthesis by Ca 2 -dependent N -acyltransferase or NAPE-PLD 
17350694NAPE-PLDNAPE-PLD1.3If not therapeutic agents per se inhibitors of NAPE-PLD FAAH AMT DAGL or MAGL could be used together with 
17350694NAPE-PLDNAPE-PLD1.3NArPE is then cleaved by NAPE-PLD a recently characterized phospholipase D which releases AEA and phosphatidic 
17350694NAPE-PLDNAPE-PLD1.3drugs that are able to modulate the AEA metabolic enzymes NAPE-PLD and FAAH might be exploited to curb neuroinflammation 
17350694nape pldnape pld1.0d dagl regulation and the role of these lipases in maintaining the endocannabinoid tone in vivo is of utmost importance as it has been for n acylphosphatidylethanolamine nape specific phospholipase d nape pld [59] and faah 60 and 61 with respect to aea.  
17350694nape pldnape pld1.0for example control of the cellular activity of aea seems to be largely dependent on its hydrolysis by faah rather than on its synthesis by ca 2+ dependent n acyltransferase or nape pld.  
17350694nape pldnape pld1.0if not therapeutic agents per se inhibitors of nape pld faah amt dagl or magl could be used together with aea or 2 ag analogs to lower the doses or to shorten the treatment necessary in vivo to observe an effect and thus to minimize the possible psychotro 
17350694nape pldnape pld1.0narpe is then cleaved by nape pld a recently characterized phospholipase d which releases aea and phosphatidic acid.  
17350694nape pldnape pld1.0on the one hand aea might control inflammatory processes by binding to trpv1 such that drugs that are able to modulate the aea metabolic enzymes nape pld and faah might be exploited to curb neuroinflammation.