HUGO ID Detailed Result 16


HUGO ID 16
Symbol SERPINA3
Name serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
#Occurrence 5
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
11173059antichymotrypsinantichymotrypsin1.0some of them code for proteins which may participate in _amp_#x3b2; amyloid protein processing or aggregation in neuritic plaques. 1 antichymotrypsin is a protease inhibitor and an acute phase protein also found in amyloid deposits in alzheimer disease brains abraham et al. 1988 .  
11173059antichymotrypsinantichymotrypsin1.0a polymorphism in the region coding for the signal peptide of the 1 antichymotrypsin gene was originally reported to confer a higher risk of alzheimer disease kamboh et al. 1995 .  
11173059antichymotrypsinantichymotrypsin1.0recent data suggest that specific polymorphism of the 1 antichymotrypsin gene may rather increase the risk for early onset alzheimer disease and that this effect is enhanced by a concomitant polymorphism of the interleukin1_amp_#x3b2; gene.  
11173059antichymotrypsinantichymotrypsin1.0 licastro and licastro . 1 antichymotrypsin release in the brains of alzheimer disease patients may be secondary to local inflammatory reactions licastro et al. 2000a and contribute to enhance _amp_#x3b2; amyloid protein aggregation ma et al.  
11173059antichymotrypsinantichymotrypsin1.0therefore polymorphism analysis of the 1 antichymotrypsin gene especially in conjunction with that of the interleukin 1 gene may provide further indications for the use of anti inflammatory drugs or interleukin 1 receptor antagonist in alzheimer disease tab