HUGO ID Detailed Result 12682


HUGO ID 12682
Symbol VEGFC
Name vascular endothelial growth factor C
#Occurrence 19
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
16104843VEGFCVEGF-C1.8VEGF family includes VEGF-A PlGF (placenta placenta growth factor VEGF-B VEGF-C VEGF-D VEGF-E and svVEGF (snake snake venom VEGF 
16104843VEGFCVEGF-C1.8VEGF-C and VEGF-D 
16104843VEGFCVEGF-C1.8VEGF-C contains a region sharing approx 30% amino acid identity with 
16104843VEGFCVEGF-C1.8Both VEGF-C and VEGF-D bind and activate VEGFR-3 (Flt-4; Flt-4 a member 
16104843VEGFCVEGF-C1.8VEGF-C also binds to NRP-2 49 ( Figure 2 
16104843VEGFCVEGF-C1.8Both VEGF-C and VEGF-D are produced as a preproprotein with long N- 
16104843VEGFCVEGF-C1.8This activation of VEGF-C and VEGF-D by proteolytic cleavage is at least partly regulated 
16104843VEGFCVEGF-C1.8Overexpression of VEGF-C in the epidermis of transgenic mice results in the development 
16104843VEGFCVEGF-C1.8In vitro VEGF-C and VEGF-D stimulate the migration and mitogenesis of cultured endothelial 
16104843VEGFCVEGF-C1.8A recent study using VEGF-C mice has demonstrated that VEGF-C is required for the initial 
16104843VEGFCVEGF-C1.8A recent study using VEGF-C mice has demonstrated that VEGF-C is required for the initial steps in lymphatic development and 
16104843VEGFCVEGF-C1.8for the initial steps in lymphatic development and that both VEGF-C alleles are required for normal lymphatic development 52 
16104843VEGFCVEGF-C1.8Thus VEGF-C is the paracrine factor essential for lymphangiogenesis 
16104843VEGFCVEGF-C1.8VEGF-E and svVEGFs as well as the processed form of VEGF-C and VEGF-D 
16104843VEGFCVEGF-C1.8VEGFR-3 is a 195 kDa high-affinity receptor for VEGF-C and VEGF-D 
16104843VEGFCVEGF-C1.8Furthermore overexpression of a VEGFR-3-specific mutant of VEGF-C (VEGF-C VEGF-C 156S in the skin induces the growth of 
16104843VEGFCVEGF-C1.8Furthermore overexpression of a VEGFR-3-specific mutant of VEGF-C (VEGF-C VEGF-C 156S in the skin induces the growth of lymphatic vessels 
16104843VEGFCVEGF-C1.8whereas NRP-2 can bind VEGF 145 VEGF 165 PlGF-2 and VEGF-C 
16104843VEGFCVEGF-C1.8family consists of VEGF-A PlGF (placenta placenta growth factor VEGF-B VEGF-C VEGF-D VEGF-E and snake venom VEGF