HUGO ID Detailed Result 11920

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
12843244	FAS	Fas	0.3	(Raoul Raoul et al. 2002 although the critical role of Fas pathway in mediating motor neuron degeneration has not been evaluated
14960605	FAS	Fas	0.6	et al. 1998 cytoskeletal abnormalities (Wong Wong et al. 1995 Fas ligand (FasL)-mediated FasL -mediated death (Raoul Raoul et al. 2002
15572176	FAS	Fas-ligand	0.6	pro-apoptotic mediators such as nerve growth factor (NGF) NGF or Fas-ligand a mechanism that may serve to eliminate vulnerable motor neurons
15572176	FAS	Fas	0.6	by motor neurons in response to trophic factor deprivation 35 Fas pathway activation 101 or loading with zinc-deficient SOD-1 36
15572176	FAS	Fas	0.6	makes the cells vulnerable to undergo apoptosis in response to Fas ligand (FasL) FasL 39
15572176	FAS	Fas	0.6	Motor neurons co-express Fas and FasL during the embryonic period of naturally occurring cell
15572176	FAS	Fas	0.6	in motoneuron survival were observed in mutant mice deficient for Fas signaling 133
15572176	FAS	Fas	0.6	In contrast Fas signaling has been implicated in motor neuron death induced by
15572176	FAS	Fas	0.6	mutations G37R G85R or G93A display an increased susceptibility to Fas signaling 99 and 101
15572176	FAS	Fas	0.6	The apoptotic pathway activated by Fas seems to be specific for motor neurons requiring co-activation of
15572176	FAS	Fas	0.6	neuron A which upregulates the expression of nNOS p75 NTR Fas cytokines and trophic factors
16510725	FAS	Fas	2.1	to the events that take place when FasL binds to Fas then death-inducing signaling complex (DISC) DISC will form and caspase-8
16510725	FAS	Fas-associated	2.1	receptors was also present A study using RPAs showed increased Fas-associated death domain (FADD) FADD and TNF-alpha receptor p55 at 80
16510725	FAS	Fas	2.1	Fas triggers cell death in embryonic motoneurons by a pathway requiring
16510725	FAS	Fas	2.1	FasL works in a similar way by binding to Fas/CD95 Fas CD95 receptor and activate it to cause FADD ligation and
16510725	CD95	CD95	2.1	works in a similar way by binding to Fas/CD95 Fas CD95 receptor and activate it to cause FADD ligation and DISC
16624536	FAS	Fas	0.6	motor neuron death via TNF--mediated apoptotic mechanisms 35 and by Fas ligand or NO-induced apoptotic pathways 36
16624536	FAS	Fas-triggered	0.6	transgenic mice exhibit an increased susceptibility to activation of a Fas-triggered cell death pathway that is unique to motor neurons and
16624536	FAS	Fas	0.6	explanation for the sensitivity of motor neurons in particular to Fas ligand and NO-triggered cell death mediated at least in part
16624536	FAS	Fas	0.6	phosphatidylinositol-3 kinase/protein kinase protein kinase B pathway fractalkine will inhibit Fas ligand-induced microglial apoptosis through down-regulation of the pro-apoptotic function of
16624536	FAS	Fas-associated	0.6	death domain (TRADD) TRADD that can then interact with the Fas-associated death domain to activate caspase 8 leading to downstream activation
16624536	FAS	Fas	0.6	Fas ligand and TNF-produced by reactive astrocytes can also activate death
16624536	FAS	Fas	0.6	Raoul et al. ALS motor neurons are particularly susceptible to Fas signaling and the apoptotic pathway implicated is motor neuron-specific 36
17015226	FAS	Fas-ligand	0.3	Microglial cells could therefore be an important player in a Fas-ligand (FasL)-induced FasL -induced apoptosis pathway within motor neurons that is
17015226	FAS	Fas	0.3	been proposed as a motor-neuron-specific cell-death pathway downstream of the Fas death receptor
17015226	FAS	Fas	0.3	Increased susceptibility to death triggered by the Fas receptor requires nitric oxide the Fas death domain-associated protein Daxx
17015226	FAS	Fas	0.3	death triggered by the Fas receptor requires nitric oxide the Fas death domain-associated protein Daxx and p38 kinase activation which subsequently
17555556	FAS	Fas	0.6	Other studies have shown that nitric oxide can induce Fas signaling in mutant SOD1 motoneurons which resulted in mutant SOD1
17555556	FAS	Fas-triggered	0.6	Additionally up-regulation of nNOS was required in this Fas-triggered motoneuron death ( Raoul et al 2002 2006